mRNA: Fulfilling the Promise of Gene Therapy

Gene therapy fulfilling its promise.

From its earliest conception, gene therapy held the promise of correcting inherited diseases by inserting a normal copy of the relevant gene into somatic cells.1 Common monogenic diseases of blood cells, such as sickle cell disease or β-thalassemia, were originally considered important candidates for gene therapy because they were well understood at the molecular level and because the target ce...

Fulfilling the promise of evidence-based medicine.

Why should wait for some days to get or receive the fulfilling the promise of evidence based medicine book that you order? Why should you take it if you can get the faster one? You can find the same book that you order right here. This is it the book that you can receive directly after purchasing. This fulfilling the promise of evidence based medicine is well known book in the world, of course ...

Fulfilling the Promise of the Cognitive Neurosciences

The paper by Meyer-Lindenberg and colleagues in this issue of Neuron provides strong evidence that the absence of one or more genes in Williams syndrome leads to highly circumscribed pathology in the dorsal visual stream. This program of research demonstrates that neurocognitive architecture follows the same principles in typical and atypical development.

Fulfilling the promise of percutaneous angioplasty.

It is ironic that in 1964, Dotters’ initial application of percutaneous transluminal angioplasty (PTA) targeted femoral-popliteal stenoses. Now, nearly 4 decades later, although angioplasty has gained wide acceptance as a firstline treatment for diseased coronary, iliac, and renal arteries, its role in femoral-popliteal vessels remains controversial and poorly defined. The initial PTA procedure...

Fulfilling the promise of Mendelian randomization